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Southern Caribbean Cruise 1 Night • Colón, Panama • Serenade of the Seas



Itinerary

Cruise Overview 

Day 1 Sat, 18 Apr Colón, Panama Departs at 4:00 pm

Day 2 Sun, 19 Apr Cartagena, Colombia Arrives at 9:00 am

Cruise Overview 

ONX CTG 1200x430

Climb aboard Serenade of the Seas for more thrills, chill and wows than you thought you could fit into a vacation. This action-packed ship departs from Colón, Panama on your cruise to Caribbean. Get ready for an epic getaway.

Side View of Serenade of the Seas Cruise Visiting Bermuda, Norwegian Fjords, Scandinavia
Men and Kids Enjoying a Game of Basketball on the Sports Court

Day 1 Sat, 18 Apr 2026 Colón, Panama Departs at 4:00 pm

Fortifications on the Caribbean Side of Panama in Colon
Wild two-toed sloth hanging on tree in Colon Island, Bocas del Toro, Panama.
View of the Santiago Fortification in Panama
Tropical paradise of sandy beaches with clear blue water in Panama
View at Palm trees, sea and houses in Isla Grande shore. Colon province, Panama
Tropical eco resort with thatched cabins over the sea, Colon island
A cruise from Colon gives you the chance to explore this exciting, small Caribbean province in Panama that’s packed with natural splendor and historical gems. For incredible views, trek through the tropical forests of Portobelo National Park to the impressive 17th century Fort San Lorenzo, which was overtaken by Henry Morgan’s pirates. Visit the town of La Guaira to fuel your senses with traditional dishes, artwork from local artisans, Calypso music and Congo dances. And be sure to check out the Agua Clara Visitor’s Center before you cruise to get a close look at the inner workings of the Panama Canal considered an engineering marvel.
Your ship departs promptly at 4:00 pm, so plan to arrive at least 2-3 hours early to account for checking in and boarding protocols. During this time, many of the ship's amenities are open and operating, so feel free to start your vacation early.
Travel Tips
1
Only in Panama can you watch the sun rise on the Pacific Ocean and set on the Atlantic Ocean. All it takes is a 50-mile taxi ride from one side of the country to the other.

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Day 2 Sun, 19 Apr 2026 Cartagena, Colombia Arrives at 9:00 am

Close up view of the Church of St. Peter Claver in Cartagena, Colombia
Beautiful turquoise water at Playa Blanca near Cartagena, Colombia
Church of St. Peter Claver in Cartagena, Colombia
Close up view of the Church of St. Peter Claver in Cartagena, Colombia
Castillo de San Felipe de Barajas castle in Cartagena de Indias, Colombia.
Sun ray during sunrise in the streets of Cartagena, Colombia
When you cruise out of Cartagena de Indias it’s worth taking a few days to explore its beautiful beaches, colorful architecture and a lively culture as enchanting as the city itself. After you cruise, take a day trip to Playa Blanca — considered one of the most beautiful beaches in Colombia — and enjoy delicious local dishes like fresh fish, coconut rice and arepa de huevo. Or catch scenic views from the Plaza de Bolivar at the heart of the historical sector and weave through the underground passages of Castillo de San Felipe de Barajas. And remember, a vacation from Cartagena is not complete without dancing to the tropical rhythms of cumbia. Hop on a multicolored chiva (party bus) or mingle with locals at upbeat bars around the city.
The cruise might have ended, but there are still some great activities to enjoy in the area. If you flew into this port, be mindful of your departure flight time and plan accordingly.
Travel Tips
1
Don't confuse Cartagena, Spain, and Cartagena, Colombia, while planning your trip!

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Your ship:

Serenade of the Seas

Serenade of the Seas Alaska Landscape Aerial
Serenade of the Seas Main Dining Room
Man playing mini golf on a cruise ship open deck.
Chefs Table Crab Wine Tasting
Vintages Wine Friends Enjoying Appetizers
Friends Diving in The Pool
Italian salami, prosciutto, roasted peppers, olives & Gambonzola cheese. Best cruise dining at Giovanni's Table restaurant.
From poolside movie nights and jaw dropping entertainment, to game changing flavors prepared to please your palate, all paths lead to discovery onboard Serenade of the Seas®.
Learn more about the ship

Ship highlights

What’s included with your vacation

Your vacation essentials are always included. Quench your thirst with water, coffee, juice and tea options available at no charge. Indulge in many delicious free dining options onboard. You can also enjoy jaw-dropping entertainment like live shows, live music, themed dance parties and more at no additional cost.

Suites come with extra amenities and inclusions.

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  • Standard beverages like water, coffee, juice and tea options
  • Food and snacks at our cafes and buffets
  • Shows, live music, and entertainment
  • Most onboard experiences

Snag these upgrades at an additional cost

  • World-class dining at speciality restaurants
  • Cocktails, specialty coffees, sodas and bottled water
  • Wi-Fi to stay connected at sea
  • Spa treatments
  • Shore excursions
  • Professional photography
  • Royal Babies and Tots℠ Nursery
  • Laundry services